NASA has developed a new technique to spot osteoporosis at its earliest stages. With bone loss a major problem for astronauts due to the microgravity in space, NASA developed this with them in mind. Currently, osteoporosis can go undected for years, only being diagonsed with scans after weakening of the bones has let to a fracture. The new test looks for traces of bone calcium in the urine which doesnt only identify bone loss, but can also give direct measurements of net bone loss. Through the study of calcium isotopes (different atoms of the element derived from bone each with their own specific number of neutrons), scientist were able to detect that the balance or abundance of the different isotopes change when bone is destroyed or formored. The changes in the isotopes can indicate early change in bone density. The technique was put to test, and found that it was able to detect bone loss after as little as one week of bed rest.
The next step is to see if it can work as expected in patients with bone altering disease, which would give this test clinical application. It is believe that this test can also be used to monitor other diseases that affect the bones, one of which is cancer. The possible ability to detect these diseases earlier and monitor some diseases with this test would be a great medical advancement. This technique also increases our understanding of bone disease, which may lead to other break through medical treatments or techniques to identify bone diseases.
http://www.bbc.co.uk/news/health-18240047